All 59 peptides in the guide

Each page covers how the peptide works, evidence by goal, reported dosing, side effects, legal status and sources. Educational reference, not medical advice.

GLP-1 & incretin drugs

• Semaglutide FDA-approved
• Tirzepatide FDA-approved
• Retatrutide Investigational (Phase 3 positive)
• Liraglutide FDA-approved (generic available)
• Orforglipron FDA-approved (Apr 2026)
• Dulaglutide & Exenatide FDA-approved
• Mazdutide Approved in China (2025); not US
• Survodutide Investigational (Phase 3)
• Pemvidutide Investigational (Phase 2/3)
• MariTide Investigational (Phase 3)

Amylin analogs

• Cagrilintide Under FDA review (as CagriSema)
• Amycretin Investigational (Phase 3)
• Eloralintide & Petrelintide Investigational (Phase 2/3)

Melanocortin (libido, tanning, appetite)

• Setmelanotide FDA-approved (genetic obesity only)
• PT-141 (Bremelanotide) FDA-approved (women's low desire)
• Melanotan II Not approved; health-agency warnings
• Afamelanotide FDA-approved (EPP)

Growth hormone axis

• Tesamorelin FDA-approved (HIV visceral fat)
• CJC-1295 Not approved; research use
• Ipamorelin Not approved; research use
• Sermorelin Formerly FDA-approved; available via compounding
• GHRP-2 & GHRP-6 Not approved in US; research use
• MK-677 (Ibutamoren) Not approved; research use
• IGF-1 LR3 Not approved; research use

Tissue repair

• BPC-157 Not approved; US compounding decision pending
• TB-500 / Thymosin Beta-4 Not approved; US compounding decision pending
• GHK-Cu Cosmetic ingredient; injectable not approved
• ARA-290 (Cibinetide) Investigational (Phase 2)

Nutritional peptides

• Collagen peptides Dietary supplement
• Glutathione Supplement; IV via clinics
• Carnosine & Anserine Dietary supplement
• Lactotripeptides (VPP/IPP) Food / supplement

Immune & anti-inflammatory

• Thymosin Alpha-1 Approved in 30+ countries; US status in flux
• LL-37 Not approved; US compounding restricted
• KPV Not approved; US compounding decision pending
• VIP Not approved for these uses
• Icotrokinra FDA-approved (Mar 2026)

Gut

• Larazotide Investigational (Phase 3 stopped)
• Linaclotide FDA-approved
• Teduglutide FDA-approved

Brain & mood

• Selank Approved in Russia; not US
• Semax Approved in Russia; not US
• Dihexa Not approved; research use
• Cerebrolysin Approved in ~50 countries; not US
• DSIP Not approved; research use

Longevity & mitochondria

• Epitalon Not approved; US compounding decision pending
• MOTS-c Not approved; US compounding decision pending
• SS-31 (Elamipretide) FDA-approved (Barth syndrome, 2025)
• Khavinson bioregulators Registered in Russia; not approved elsewhere

Topical cosmetic

• Argireline Cosmetic ingredient
• Matrixyl Cosmetic ingredient

Reproductive & social hormones

• Kisspeptin-10 Research use (human studies)
• Gonadorelin Approved (diagnostic/fertility pump, outside US)
• Oxytocin FDA-approved (labor); intranasal off-label
• Desmopressin FDA-approved

Fat metabolism

• AOD-9604 Not approved; US compounding restricted

Bone

• Teriparatide FDA-approved
• Calcitonin (salmon) Approved; use restricted

Heart & cholesterol

• Enlicitide FDA-approved (Jul 2026)